Sulfonamide ifite ibyiza bya antibacterial spécran, ibintu bihamye, igiciro gito hamwe nimyiteguro itandukanye yo guhitamo. Imiterere shingiro ya sulfonamide ni p-sulfanilamide. Irashobora kubangamira synthèse ya aside folike ya bagiteri kandi ikagira ingaruka kumikurire no kubyara, bityo bikabuza bagiteri nyinshi za Gram-positif na bagiteri zimwe na zimwe mbi.

Indwara ya bagiteri yunvikana cyane na sulfa harimo: Streptococcus, Pneumococcus, Salmonella, nibindi, kandi byoroheje bikabije ni: Staphylococcus, Escherichia coli, Pasteurella, Shigella, Listeria, Actinomyces na Treponema hyodysenteriae Yumva kandi sulfonamide; ikora neza kurwanya protozoa zimwe na zimwe nka coccidia. Indwara ya bacteri yunvikana na sulfonamide irashobora guteza imbere guhangana.

Mugukoresha nyabyo, sulfonamide ikoreshwa kenshi hamwe nibindi biyobyabwenge. Inyinshi mu ngaruka mbi zo gukoresha igihe kirekire cyo gukoresha sulfonamide hakiri kare ni ihungabana ryinkari, kubura impyiko no kugabanya ibiryo.

Kugirango ugabanye uburozi bwayo ningaruka, ubanza, dosiye igomba kuba ikwiye, kandi ntigomba kwiyongera cyangwa kugabanuka uko bishakiye. Niba ibipimo ari binini cyane, bizongera uburozi ningaruka, kandi niba dosiye ari nto cyane, ntabwo bizagira ingaruka zo kuvura gusa, ahubwo bizatera bagiteri zitera indwara gutera imiti irwanya ibiyobyabwenge. Icya kabiri, koresha nibindi biyobyabwenge, nka amproline na sulfonamide synergiste, kugirango ugabanye dosiye. Icya gatatu, niba formula ibemerera, ingano ingana na sodium bicarbonate irashobora kongerwamo. Icya kane, bagiteri zirashobora gutanga impamyabumenyi zitandukanye zo kurwanya imiti ya sulfa, iyo rero irwanya imiti runaka ya sulfa, ntibikwiye ko uhindukirira undi muti wa sulfa. Muri rusange, ibipimo byambere byibiyobyabwenge bya sulfa bigomba gukuba kabiri, kandi nyuma yigihe gikaze, imiti igomba gutsimbarara kuyifata iminsi 3-4 mbere yuko ihagarara.